WebPrevious studies in patients after HTX detected advantageous effects regarding renal function of a tacrolimus (TAC)-based vs cyclosporine-A (CSA)-based immunosuppression (in combination with mycophenolate mofetil). ... Everolimus: efficacy and safety in cardiac transplantation. Expert Opin Drug Saf. 2010;9(5):843–854. 37. Web14 jan. 2015 · Tacrolimus is an immunosuppressive agent used to prevent graft rejection after renal transplantation [].Because tacrolimus has a narrow therapeutic index, high intra- and inter-individual pharmacokinetic variability and a poor correlation between dosage and blood concentration, therapeutic drug monitoring (TDM) is an important tool for …
A Prediction Model for Tacrolimus Daily Dose in Kidney Transplant ...
Web1 sep. 2024 · Minimal data are currently available on the use and safety of remdesivir in this at-risk population. 24 Here, we present the results of a Spanish multicenter study … WebObjectives Tacrolimus is one of the three basic immunosuppressants used following kidney transplantation, and its plasma concentration is susceptible to antifungal drugs. Abnormal tacrolimus concentrations may lead to adverse outcomes for patients. Adjustment of the tacrolimus dose after administering antifungal drugs to patients with … cantilevered eaves
Implementation of Clinical CYP3A Genotyping for Tacrolimus …
WebIntroduction: Tacrolimus-based immunosuppression remains the immunosuppressive drug of choice in kidney transplantation. Areas covered: Its safety profile is closely … Web27 mei 2024 · Introduction. Tacrolimus, a calcineurin inhibitor, is a widely acceptable used immunosuppressive drug in kidney transplant recipients (KTRs). The narrow therapeutic index of tacrolimus leads to a very close edge between therapeutic and toxic blood concentration ().An inappropriate regimen of tacrolimus in the early phase after … WebIn kidney transplant recipients (KTRs), uraemia-induced central nervous system damage partly subsides, while the long-lasting exposure to tacrolimus may cause pathologic visual evoked potentials (VEP) findings, which have not been investigated yet. Thus, the aim of the present study was to assess the effect of tacrolimus maintenance treatment on … cantilevered display rack